Reactions of secondary propargylamines with heteroallenes for the synthesis of diverse heterocycles

Vsevolod A. Peshkov, Olga P. Pereshivko, Anton A. Nechaev, Anatoly A. Peshkov, Erik V. Van Der Eycken

Research output: Contribution to journalReview article

24 Citations (Scopus)

Abstract

This focused review aims to summarize recent developments in the processes involving additions of secondary propargylamines to various heteroallenes and subsequent transition metal-catalyzed or electrophile-mediated cyclizations. The utility of this convenient and tunable strategy spans from the carbon dioxide fixation and target-oriented synthesis of complex natural and biologically active products to the generation of extended synthetic libraries of diverse oxygen-, nitrogen- and sulfur-containing heterocycles. For comparative purposes, the analogous transformations of propargylic alcohols are also highlighted in this account.

Original languageEnglish
Pages (from-to)3861-3898
Number of pages38
JournalChemical Society Reviews
Volume47
Issue number11
DOIs
Publication statusPublished - Jun 7 2018
Externally publishedYes

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Cyclization
Sulfur
Carbon Dioxide
Transition metals
Nitrogen
Alcohols
Oxygen
propargylamine

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Reactions of secondary propargylamines with heteroallenes for the synthesis of diverse heterocycles. / Peshkov, Vsevolod A.; Pereshivko, Olga P.; Nechaev, Anton A.; Peshkov, Anatoly A.; Van Der Eycken, Erik V.

In: Chemical Society Reviews, Vol. 47, No. 11, 07.06.2018, p. 3861-3898.

Research output: Contribution to journalReview article

Peshkov, Vsevolod A. ; Pereshivko, Olga P. ; Nechaev, Anton A. ; Peshkov, Anatoly A. ; Van Der Eycken, Erik V. / Reactions of secondary propargylamines with heteroallenes for the synthesis of diverse heterocycles. In: Chemical Society Reviews. 2018 ; Vol. 47, No. 11. pp. 3861-3898.
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