TY - JOUR
T1 - Recent advances in homogeneous base-metal-catalyzed transfer hydrogenation reactions
AU - Baidilov, Daler
AU - Hayrapetyan, Davit
AU - Khalimon, Andrey Y.
N1 - Funding Information:
D.H. and A.Y.K. would like to thank Nazarbayev University for financial support via FDCRG grants (Nr. 240919FD3905 to D. H. and Nr. 240919FD3911 to A.Y.K.).
Funding Information:
D.H. and A.Y.K. would like to thank Nazarbayev University for financial support via FDCRG grants (Nr. 240919FD3905 to D. H. and Nr. 240919FD3911 to A.Y.K.).
Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/10/8
Y1 - 2021/10/8
N2 - Owing to availability of various hydrogen sources, operational simplicity, and mild reaction conditions, catalytic transfer hydrogenation (TH) has emerged as an appealing alternative for the direct hydrogenation reactions with H2 gas. Conventional TH catalysts are based on noble metals, such as Ru, Rh, and Ir, which are toxic and expensive due to their limited availability. Current research in this area is oriented towards the development of more sustainable catalysts utilizing abundant 1st row transition metals with readily accessible ligand platforms. During the past few decades, many novel examples of such systems appeared in the literature, expanding not only the number of catalyst surrogates but also the scope of unsaturated substrates, opening new venues for TH in organic synthesis. This review aims to provide an update on recent advances in homogeneous TH reactions catalyzed by base-metal (Mn, Fe, Co and Ni) complexes. Special attention is paid to selectivity and the mechanisms of such transformations.
AB - Owing to availability of various hydrogen sources, operational simplicity, and mild reaction conditions, catalytic transfer hydrogenation (TH) has emerged as an appealing alternative for the direct hydrogenation reactions with H2 gas. Conventional TH catalysts are based on noble metals, such as Ru, Rh, and Ir, which are toxic and expensive due to their limited availability. Current research in this area is oriented towards the development of more sustainable catalysts utilizing abundant 1st row transition metals with readily accessible ligand platforms. During the past few decades, many novel examples of such systems appeared in the literature, expanding not only the number of catalyst surrogates but also the scope of unsaturated substrates, opening new venues for TH in organic synthesis. This review aims to provide an update on recent advances in homogeneous TH reactions catalyzed by base-metal (Mn, Fe, Co and Ni) complexes. Special attention is paid to selectivity and the mechanisms of such transformations.
KW - Base-metals
KW - Homogeneous catalysis
KW - Reduction
KW - Transfer hydrogenation
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U2 - 10.1016/j.tet.2021.132435
DO - 10.1016/j.tet.2021.132435
M3 - Article
AN - SCOPUS:85114737598
SN - 0040-4020
VL - 98
JO - Tetrahedron
JF - Tetrahedron
M1 - 132435
ER -
