Recreational substance use and tolerance of efavirenz in HIV-1 infected patients

F. Faggian, E. Lattuada, Massimiliano Lanzafame, D. Antolini, E. Concia, S. Vento

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


During the past few years, efavirenz has been increasingly used in the treatment of HIV1 infection. Its main side effect is a syndrome of central nervous system stimulation occurring in 40-50% of adults in the first few weeks of therapy which might be observed at increased frequency in subjects concurrently using recreational substances. We therefore conducted a single center, retrospective study in 134 patients treated with efavirenz and found no significant differences in CNS side effects or discontinuation rates between recreational substance (cocaine, ecstasy, cannabis) users and non-users. Although our study is limited, the results support the idea that efavirenz can be safely prescribed to patients using recreational substances.

Original languageEnglish
Pages (from-to)908-910
Number of pages3
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Issue number7
Publication statusPublished - Oct 1 2005

ASJC Scopus subject areas

  • Social Psychology
  • Health(social science)
  • Public Health, Environmental and Occupational Health

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