Revisiting shape selectivity in liquid chromatography for polycyclic aromatic hydrocarbons (PAHs) – six-ring and seven-ring Cata-condensed PAH isomers of molecular mass 328 Da and 378 Da

Jorge Ona Ruales, Lane C. Sander, Walter B. Wilson, Stephen A. Wise

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

The relationship of reversed-phase liquid chromatography (RPLC) retention on a polymeric C18 stationary phase and the shape of polycyclic aromatic hydrocarbons (PAHs) was investigated for three-ring to seven-ring cata-condensed isomers. We report the first RPLC separation for six-ring and seven-ring cata-condensed PAH isomers. Correlations of LC retention and shape parameters (length-to-breath ratio, L/B and thickness, T) were investigated for 2 three-ring isomers (molecular mass 178 Da), 5 four-ring isomers (molecular mass 228 Da), 11 five-ring isomers (molecular mass 278 Da), 17 six-ring isomers (molecular mass 328 Da), and 20 seven-ring isomers (molecular mass 378 Da). Significant linear correlations were found for all isomer groups (r = 0.71 to 0.94). Nonplanarity of the PAH isomers was found to influence retention (i.e., nonplanar isomers eluting earlier than expected based on L/B) and linear correlations of retention vs. T for isomer groups containing nonplanar isomers were significant (r = 0.71 to 0.86). [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)885-896
Number of pages12
JournalAnalytical and Bioanalytical Chemistry
Volume410
Issue number3
DOIs
Publication statusPublished - Jan 1 2018

Keywords

  • High molecular mass PAHs
  • Length-to-breadth ratio (L/B)
  • Nonplanarity
  • Polycyclic aromatic hydrocarbons (PAHs)
  • Reverse-phase liquid chromatography (RPLC)
  • Shape selectivity

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

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