TY - JOUR
T1 - Risks for tuberculosis in Kazakhstan
T2 - Implications for prevention
AU - Davis, A.
AU - Terlikbayeva, Assel
AU - Aifah, A.
AU - Hermosilla, S.
AU - Zhumadilov, Z.
AU - Berikova, E.
AU - Rakhimova, S.
AU - Primbetova, S.
AU - Darisheva, M.
AU - Schluger, N.
AU - El-Bassel, N.
N1 - Funding Information:
The authors would like to thank the National TB Center, Almaty, and oblast TB dispensaries in Almaty City and in the Almaty, Kyzylorda, and Kostanay oblasts, the patients with TB and their families, as well as the other participants for their assistance with this study. The study was funded by the Ministry of Education and Science, Astana, through the Center for Life Sciences, Nazarbayev University, Astana, Kazakhstan. Conflicts of interest: none declared.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - SETTING: Four regions in Kazakhstan where participants were recruited from June 2012 to May 2014. OBJECTIVE: To examine associations between incarceration history and tobacco, alcohol, and drug consumption, and human immunodeficiency virus (HIV) infection and diabetes mellitus (DM) with TB. DESIGN: This matched case-control study included 1600 participants who completed a survey on sociodemographics, history of incarceration, tobacco, alcohol and drug use, and HIV and DM diagnosis. Conditional logistic regression analysis was used to examine associations between a TB diagnosis and risk factors. RESULTS: Participants who had ever smoked tobacco (aOR 1.73, 95%CI 1.23-2.43, P ≤ 0.01), ever drank alcohol (aOR 1.41, 95%CI 1.03-1.93, P ≤ 0.05), were HIV-positive (aOR 36.37, 95%CI 2.05-646.13, P ≤ 0.05) or had DM (aOR 13.96, 95%CI 6.37-30.56, P ≤ 0.01) were more likely to have TB. CONCLUSIONS: The association between TB and tobacco use, alcohol use, HIV and DM in Kazakhstan suggests a need for comprehensive intervention and prevention approaches that also address tobacco and alcohol use, DM and HIV.
AB - SETTING: Four regions in Kazakhstan where participants were recruited from June 2012 to May 2014. OBJECTIVE: To examine associations between incarceration history and tobacco, alcohol, and drug consumption, and human immunodeficiency virus (HIV) infection and diabetes mellitus (DM) with TB. DESIGN: This matched case-control study included 1600 participants who completed a survey on sociodemographics, history of incarceration, tobacco, alcohol and drug use, and HIV and DM diagnosis. Conditional logistic regression analysis was used to examine associations between a TB diagnosis and risk factors. RESULTS: Participants who had ever smoked tobacco (aOR 1.73, 95%CI 1.23-2.43, P ≤ 0.01), ever drank alcohol (aOR 1.41, 95%CI 1.03-1.93, P ≤ 0.05), were HIV-positive (aOR 36.37, 95%CI 2.05-646.13, P ≤ 0.05) or had DM (aOR 13.96, 95%CI 6.37-30.56, P ≤ 0.01) were more likely to have TB. CONCLUSIONS: The association between TB and tobacco use, alcohol use, HIV and DM in Kazakhstan suggests a need for comprehensive intervention and prevention approaches that also address tobacco and alcohol use, DM and HIV.
KW - Alcohol
KW - Diabetes
KW - HIV
KW - Tobacco
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U2 - 10.5588/ijtld.15.0838
DO - 10.5588/ijtld.15.0838
M3 - Article
AN - SCOPUS:85007530042
VL - 21
SP - 86-92 and i-v
JO - International Journal of Tuberculosis and Lung Disease
JF - International Journal of Tuberculosis and Lung Disease
SN - 1027-3719
IS - 1
ER -