Role of neutrophils in controlling early stages of a Chlamydia trachomatis infection

Natalie Barteneva, Ida Theodor, Ellena M. Peterson, Luis M. De La Maza

Research output: Contribution to journalArticlepeer-review

89 Citations (Scopus)

Abstract

Inoculation of mice with the granulocyte-depleting monoclonal antibody RB6-8C5 showed that neutrophils are critical protective effector cells during a Chlamydia trachomatis infection. In addition, administration of monoclonal antibody 2E6 demonstrated that extravasation of neutrophils into the peritoneal cavity in response to inoculation with the C. trachomatis MoPn biovar is dependent on the surface β-2 integrin molecule CD18.

Original languageEnglish
Pages (from-to)4830-4833
Number of pages4
JournalInfection and Immunity
Volume64
Issue number11
DOIs
Publication statusPublished - Nov 5 1996
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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