SCORPION, a molecular database of scorpion toxins

K. N. Srinivasan, P. Gopalakrishnakone, P. T. Tan, K. C. Chew, B. Cheng, R. M. Kini, J. L.Y. Koh, S. H. Seah, V. Brusic

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Increasing interest in the studies of toxins and the requirements for better structural and functional annotations have created a need for improved data management in the field of toxins. The molecular database, SCORPION, contains more than 200 entries of fully referenced scorpion toxin data including primary sequences, three-dimensional structures, structural and functional annotations of scorpion toxins along with relevant literature references. SCORPION has a set of search tools that allow users to extract data and perform specific queries. These entries have been compiled from public databases and literature, cleaned of errors and enriched with additional structural and functional information. The grouping of scorpion toxins provides a basis for extending and clarifying the existing structural and functional classifications. The bioinformatics modules in SCORPION facilitate analyses aimed at classification of scorpion toxins and identification of sequence patterns associated with specific structural or functional properties of scorpion toxins. The SCORPION database is accessible via the Internet at sdmc.krdl.org.sg:8080/scorpion.

Original languageEnglish
Pages (from-to)23-31
Number of pages9
JournalToxicon
Volume40
Issue number1
DOIs
Publication statusPublished - Jan 1 2002

Keywords

  • Functional annotation
  • Homology model
  • Toxin informatics
  • Venom informatics

ASJC Scopus subject areas

  • Toxicology

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    Srinivasan, K. N., Gopalakrishnakone, P., Tan, P. T., Chew, K. C., Cheng, B., Kini, R. M., Koh, J. L. Y., Seah, S. H., & Brusic, V. (2002). SCORPION, a molecular database of scorpion toxins. Toxicon, 40(1), 23-31. https://doi.org/10.1016/S0041-0101(01)00182-9