@article{b08d55b71b414227aa62923fdd37b50f,
title = "Silver(I) Triflate-Catalyzed Protocol for the Post-Ugi Synthesis of Spiroindolines",
abstract = "A silver(I) triflate-catalyzed protocol for the post-Ugi synthesis of tetracyclic spiroindolines has been developed. The protocol worked best for indole-3-carbaldehyde-derived Ugi adducts obtained using anilines and 3-aryl propiolic acids. Thus, it is complementary to the previous cationic gold-catalyzed procedure that was developed for analogues Ugi substrates derived from aliphatic amines and 3-alkyl propiolic acids. Furthermore, we have demonstrated that under our new settings this domino Friedel-Crafts ipso cyclization / imine trapping process could be efficiently combined with the preceding four-component Ugi reaction into a two-step one-pot transformation. (Figure presented.).",
keywords = "Domino reactions, Multicomponent reactions, Nitrogen heterocycles, Silver catalysis, Spiro compounds",
author = "Manzoor Zaman and Muhammad Hasan and Peshkov, {Anatoly A.} and {Van Hecke}, Kristof and {Van der Eycken}, {Erik V.} and Pereshivko, {Olga P.} and Peshkov, {Vsevolod A.}",
note = "Funding Information: This work was supported by the start‐up fund from Soochow University (grant Q410900714), National Natural Science Foundation of China (grant 21650110445), Natural Science Foundation of Jiangsu Province of China (grant BK20160310), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) and the project of scientific and technologic infrastructure of Suzhou (grant SZS201708). M.Z. and M.H. are grateful to the Chinese Scholarship Council (CSC) for providing doctoral scholarships. K.V.H. thanks the Hercules Foundation (project AUGE/11/029 “3DSPACE: 3D Structural Platform Aiming for Chemical Excellence”) and the Special Research Fund (BOF)‐UGent (project 01 N03217) for funding. E.V.V.d.E. acknowledges the support of RUDN University through the Program 5–100. Funding Information: This work was supported by the start-up fund from Soochow University (grant Q410900714), National Natural Science Foundation of China (grant 21650110445), Natural Science Foundation of Jiangsu Province of China (grant BK20160310), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) and the project of scientific and technologic infrastructure of Suzhou (grant SZS201708). M.Z. and M.H. are grateful to the Chinese Scholarship Council (CSC) for providing doctoral scholarships. K.V.H. thanks the Hercules Foundation (project AUGE/11/029 ?3DSPACE: 3D Structural Platform Aiming for Chemical Excellence?) and the Special Research Fund (BOF)-UGent (project 01 N03217) for funding. E.V.V.d.E. acknowledges the support of RUDN University through the Program 5?100.",
year = "2020",
month = jan,
day = "7",
doi = "10.1002/adsc.201901064",
language = "English",
volume = "362",
pages = "261--268",
journal = "Advanced Synthesis and Catalysis",
issn = "1615-4150",
publisher = "Wiley-VCH Verlag",
number = "1",
}