Smart polymers for bioseparation and other biotechnological applications

I. N. Savina, I. Yu Galaev, S. V. Mikhalovsky

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

The progress in development of a number of novel products using recombinant DNA technology and cell culturing, plus the demands for high product yield whilst preserving biological activity, require novel approaches for fast and cost-effective isolation and/or purification processes. Smart polymers (SPs) with their ability to undergo considerable changes in response to external stimuli make possible the development of novel technologies for isolation and purification. In this chapter the main applications of SPs in biotechnology and, in particular, in bioseparation, are discussed. Affinity precipitation, two-phase polymer separation, using SP membranes and SP chromatographic carriers are overviewed with a presentation of recent developments and discussion of future perspectives in these areas. Application of SP as catalysts is also discussed.

Original languageEnglish
Title of host publicationSmart Polymers and their Applications
PublisherElsevier
Pages408-436
Number of pages29
ISBN (Print)9780857096951
DOIs
Publication statusPublished - Feb 2014

Keywords

  • Adsorbents
  • Affinity precipitation
  • Bioseparation
  • Catalysts
  • Chromatography
  • Membranes
  • Smart polymer
  • Two-phase systems

ASJC Scopus subject areas

  • Materials Science(all)

Fingerprint Dive into the research topics of 'Smart polymers for bioseparation and other biotechnological applications'. Together they form a unique fingerprint.

  • Cite this

    Savina, I. N., Galaev, I. Y., & Mikhalovsky, S. V. (2014). Smart polymers for bioseparation and other biotechnological applications. In Smart Polymers and their Applications (pp. 408-436). Elsevier. https://doi.org/10.1533/9780857097026.2.408