Spatial structure and antimicrobial activity of cyclopropane derivative of limonene

Daniyar Sadyrbekov, Timur Saliev, Yuri Gatilov, Ivan Kulakov, Roza Seidakhmetova, Tulegen Seilkhanov, Sholpan Askarova

Research output: Contribution to journalArticle

Abstract

A cyclopropane derivative of limonene, (1S, 4S, 6R)-7,7-dichloro-4-[(1S)-2,2-dichloro-1-methylcyclopropyl]-1-methylbicyclo [4.1.0] heptane (compound 2), was synthesized and its structure was determined by NMR and X-ray crystallographic methods. In addition, an antimicrobial activity of the compound against Gram-positive (Staphylococcus aureus, Bacillus subtilis) and Gram-negative (Escherichia coli, Pseudomonas aeruginosa) bacterial strains was also scrutinized.

Original languageEnglish
Pages (from-to)387-388
Number of pages2
JournalNatural Product Communications
Volume13
Issue number4
DOIs
Publication statusPublished - 2018

Keywords

  • Antimicrobial activity.
  • Cyclopropane derivative
  • Limonene
  • Structure
  • X-ray

ASJC Scopus subject areas

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

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