Abstract
Using the catechol Tiron as an O(-·)2 scavenger, we showed that sea sponges (Sycon sp.) produce superoxide radicals in sea water at a high rate without any stimuli added. The rate of O(-·)2 outflow from sponges to their water surroundings reaches a value of 0.5 nmol/min per sponge at pH 6.5. The generation of O(-·)2 was inhibited by Cu,Zn-superoxide dismutase, and restored by the addition of KCN. We also confirmed the abiotic production of O(-·)2 in sea water, detected earlier with a different method by Petasne and Zika [Nature 325 (1987) 516-518]. Copyright (C) 1998 Federation of European Biochemical Societies.
| Original language | English |
|---|---|
| Pages (from-to) | 201-204 |
| Number of pages | 4 |
| Journal | FEBS Letters |
| Volume | 434 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - Aug 28 1998 |
| Externally published | Yes |
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Keywords
- Electron paramagnetic resonance
- Free radical
- Sea animal
- Sea water
- Sponge
- Superoxide
ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology
Cite this
Superoxide radical production by sponges Sycon sp. / Peskin, Alexander V.; Labas, Yulii A.; Tikhonov, Alexander N.
In: FEBS Letters, Vol. 434, No. 1-2, 28.08.1998, p. 201-204.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Superoxide radical production by sponges Sycon sp
AU - Peskin, Alexander V.
AU - Labas, Yulii A.
AU - Tikhonov, Alexander N.
PY - 1998/8/28
Y1 - 1998/8/28
N2 - Using the catechol Tiron as an O(-·)2 scavenger, we showed that sea sponges (Sycon sp.) produce superoxide radicals in sea water at a high rate without any stimuli added. The rate of O(-·)2 outflow from sponges to their water surroundings reaches a value of 0.5 nmol/min per sponge at pH 6.5. The generation of O(-·)2 was inhibited by Cu,Zn-superoxide dismutase, and restored by the addition of KCN. We also confirmed the abiotic production of O(-·)2 in sea water, detected earlier with a different method by Petasne and Zika [Nature 325 (1987) 516-518]. Copyright (C) 1998 Federation of European Biochemical Societies.
AB - Using the catechol Tiron as an O(-·)2 scavenger, we showed that sea sponges (Sycon sp.) produce superoxide radicals in sea water at a high rate without any stimuli added. The rate of O(-·)2 outflow from sponges to their water surroundings reaches a value of 0.5 nmol/min per sponge at pH 6.5. The generation of O(-·)2 was inhibited by Cu,Zn-superoxide dismutase, and restored by the addition of KCN. We also confirmed the abiotic production of O(-·)2 in sea water, detected earlier with a different method by Petasne and Zika [Nature 325 (1987) 516-518]. Copyright (C) 1998 Federation of European Biochemical Societies.
KW - Electron paramagnetic resonance
KW - Free radical
KW - Sea animal
KW - Sea water
KW - Sponge
KW - Superoxide
UR - http://www.scopus.com/inward/record.url?scp=0031697805&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031697805&partnerID=8YFLogxK
U2 - 10.1016/S0014-5793(98)00981-8
DO - 10.1016/S0014-5793(98)00981-8
M3 - Article
VL - 434
SP - 201
EP - 204
JO - FEBS Letters
JF - FEBS Letters
SN - 0014-5793
IS - 1-2
ER -