Abstract
We have discovered that quercetin, once coated on the CdSe and CdSe-CdS quantum dots (QDs), becoming highly water soluble. In the present work, we have successfully synthesized CdSe/CdS/N-Acetyl-L-Cysteine(NAC)/Quercetin nano-composites in the aqueous solution. The products were characterized using UV-vis spectroscopy, X-ray powder diffraction, fluorescence spectroscopy, and Fourier transform infrared spectroscopy. The transmission electron microscopy (TEM) tests indicated that our nano-composite products are highly stable with homogeneous particle size and great monodispersity. Quercetin coated nano-composite CdSe/CdS/NAC/Quercetin showed different fluorescence behavior from that of CdSe/CdS/NAC. Most amazingly, the synthesized CdSe/CdS/NAC/Quercetin nano-composite exhibits strong antibacterial activity. The combination of the strong fluorescence and its antibacterial activity makes the quercetin modified quantum dots as a potential candidate for cancer targeted therapy and other cancer treatments.
| Original language | English |
|---|---|
| Pages (from-to) | 136-141 |
| Number of pages | 6 |
| Journal | Journal of the Korean Chemical Society |
| Volume | 59 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 20 2015 |
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Keywords
- CdSe/CdS
- Core-shell
- Quantum dots
- Quercetin
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Chemistry (miscellaneous)
Cite this
Synthesis and characterization of CdSe/CdS/N-acetyl-l-cysteine/quercetin nano-composites and their antibacterial performance. / Wang, Kunjie; Li, Mingliang; Li, Hongxia; Guan, Feng; Zhang, Deyi; Feng, Huixia; Fan, Haiyan.
In: Journal of the Korean Chemical Society, Vol. 59, No. 2, 20.04.2015, p. 136-141.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Synthesis and characterization of CdSe/CdS/N-acetyl-l-cysteine/quercetin nano-composites and their antibacterial performance
AU - Wang, Kunjie
AU - Li, Mingliang
AU - Li, Hongxia
AU - Guan, Feng
AU - Zhang, Deyi
AU - Feng, Huixia
AU - Fan, Haiyan
PY - 2015/4/20
Y1 - 2015/4/20
N2 - We have discovered that quercetin, once coated on the CdSe and CdSe-CdS quantum dots (QDs), becoming highly water soluble. In the present work, we have successfully synthesized CdSe/CdS/N-Acetyl-L-Cysteine(NAC)/Quercetin nano-composites in the aqueous solution. The products were characterized using UV-vis spectroscopy, X-ray powder diffraction, fluorescence spectroscopy, and Fourier transform infrared spectroscopy. The transmission electron microscopy (TEM) tests indicated that our nano-composite products are highly stable with homogeneous particle size and great monodispersity. Quercetin coated nano-composite CdSe/CdS/NAC/Quercetin showed different fluorescence behavior from that of CdSe/CdS/NAC. Most amazingly, the synthesized CdSe/CdS/NAC/Quercetin nano-composite exhibits strong antibacterial activity. The combination of the strong fluorescence and its antibacterial activity makes the quercetin modified quantum dots as a potential candidate for cancer targeted therapy and other cancer treatments.
AB - We have discovered that quercetin, once coated on the CdSe and CdSe-CdS quantum dots (QDs), becoming highly water soluble. In the present work, we have successfully synthesized CdSe/CdS/N-Acetyl-L-Cysteine(NAC)/Quercetin nano-composites in the aqueous solution. The products were characterized using UV-vis spectroscopy, X-ray powder diffraction, fluorescence spectroscopy, and Fourier transform infrared spectroscopy. The transmission electron microscopy (TEM) tests indicated that our nano-composite products are highly stable with homogeneous particle size and great monodispersity. Quercetin coated nano-composite CdSe/CdS/NAC/Quercetin showed different fluorescence behavior from that of CdSe/CdS/NAC. Most amazingly, the synthesized CdSe/CdS/NAC/Quercetin nano-composite exhibits strong antibacterial activity. The combination of the strong fluorescence and its antibacterial activity makes the quercetin modified quantum dots as a potential candidate for cancer targeted therapy and other cancer treatments.
KW - CdSe/CdS
KW - Core-shell
KW - Quantum dots
KW - Quercetin
UR - http://www.scopus.com/inward/record.url?scp=84926194874&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84926194874&partnerID=8YFLogxK
U2 - 10.5012/jkcs.2015.59.2.136
DO - 10.5012/jkcs.2015.59.2.136
M3 - Article
VL - 59
SP - 136
EP - 141
JO - Journal of the Korean Chemical Society
JF - Journal of the Korean Chemical Society
SN - 1017-2548
IS - 2
ER -