Synthesis and characterization of CdSe/CdS/N-acetyl-l-cysteine/quercetin nano-composites and their antibacterial performance

Kunjie Wang, Mingliang Li, Hongxia Li, Feng Guan, Deyi Zhang, Huixia Feng, Haiyan Fan

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    We have discovered that quercetin, once coated on the CdSe and CdSe-CdS quantum dots (QDs), becoming highly water soluble. In the present work, we have successfully synthesized CdSe/CdS/N-Acetyl-L-Cysteine(NAC)/Quercetin nano-composites in the aqueous solution. The products were characterized using UV-vis spectroscopy, X-ray powder diffraction, fluorescence spectroscopy, and Fourier transform infrared spectroscopy. The transmission electron microscopy (TEM) tests indicated that our nano-composite products are highly stable with homogeneous particle size and great monodispersity. Quercetin coated nano-composite CdSe/CdS/NAC/Quercetin showed different fluorescence behavior from that of CdSe/CdS/NAC. Most amazingly, the synthesized CdSe/CdS/NAC/Quercetin nano-composite exhibits strong antibacterial activity. The combination of the strong fluorescence and its antibacterial activity makes the quercetin modified quantum dots as a potential candidate for cancer targeted therapy and other cancer treatments.

    Original languageEnglish
    Pages (from-to)136-141
    Number of pages6
    JournalJournal of the Korean Chemical Society
    Volume59
    Issue number2
    DOIs
    Publication statusPublished - Apr 20 2015

    Fingerprint

    Acetylcysteine
    Quercetin
    Composite materials
    Semiconductor quantum dots
    Fluorescence
    Oncology
    Fluorescence spectroscopy
    Ultraviolet spectroscopy
    X ray powder diffraction
    Fourier transform infrared spectroscopy
    Particle size
    Transmission electron microscopy
    Water

    Keywords

    • CdSe/CdS
    • Core-shell
    • Quantum dots
    • Quercetin

    ASJC Scopus subject areas

    • Chemical Engineering (miscellaneous)
    • Chemistry (miscellaneous)

    Cite this

    Synthesis and characterization of CdSe/CdS/N-acetyl-l-cysteine/quercetin nano-composites and their antibacterial performance. / Wang, Kunjie; Li, Mingliang; Li, Hongxia; Guan, Feng; Zhang, Deyi; Feng, Huixia; Fan, Haiyan.

    In: Journal of the Korean Chemical Society, Vol. 59, No. 2, 20.04.2015, p. 136-141.

    Research output: Contribution to journalArticle

    Wang, Kunjie ; Li, Mingliang ; Li, Hongxia ; Guan, Feng ; Zhang, Deyi ; Feng, Huixia ; Fan, Haiyan. / Synthesis and characterization of CdSe/CdS/N-acetyl-l-cysteine/quercetin nano-composites and their antibacterial performance. In: Journal of the Korean Chemical Society. 2015 ; Vol. 59, No. 2. pp. 136-141.
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    AU - Zhang, Deyi

    AU - Feng, Huixia

    AU - Fan, Haiyan

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