Synthesis and characterization of CdSe/CdS/N-acetyl-l-cysteine/quercetin nano-composites and their antibacterial performance

Kunjie Wang, Mingliang Li, Hongxia Li, Feng Guan, Deyi Zhang, Huixia Feng, Haiyan Fan

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

We have discovered that quercetin, once coated on the CdSe and CdSe-CdS quantum dots (QDs), becoming highly water soluble. In the present work, we have successfully synthesized CdSe/CdS/N-Acetyl-L-Cysteine(NAC)/Quercetin nano-composites in the aqueous solution. The products were characterized using UV-vis spectroscopy, X-ray powder diffraction, fluorescence spectroscopy, and Fourier transform infrared spectroscopy. The transmission electron microscopy (TEM) tests indicated that our nano-composite products are highly stable with homogeneous particle size and great monodispersity. Quercetin coated nano-composite CdSe/CdS/NAC/Quercetin showed different fluorescence behavior from that of CdSe/CdS/NAC. Most amazingly, the synthesized CdSe/CdS/NAC/Quercetin nano-composite exhibits strong antibacterial activity. The combination of the strong fluorescence and its antibacterial activity makes the quercetin modified quantum dots as a potential candidate for cancer targeted therapy and other cancer treatments.

Original languageEnglish
Pages (from-to)136-141
Number of pages6
JournalJournal of the Korean Chemical Society
Volume59
Issue number2
DOIs
Publication statusPublished - Apr 20 2015

Keywords

  • CdSe/CdS
  • Core-shell
  • Quantum dots
  • Quercetin

ASJC Scopus subject areas

  • Chemistry (miscellaneous)
  • Chemical Engineering (miscellaneous)

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