Synthesis, characterization and antimicrobial activity of silver nanoparticles: Agn(NALC)m and Agn(GSHR) m

Kunjie Wang, Yanping Wu, Hongxia Li, Mingliang Li, Deyi Zhang, Huixia Feng, Haiyan Fan

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


We developed a one-step synthesis method of N-acetyl-l-cysteine and glutathione reduced protected Ag nanoparticles powder, and present a thorough characterization of the synthesized nanoparticles. The morphology and surface properties of Ag nanoparticles were obtained by transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FT-IR), the optical properties and stability of these Ag nanoparticles in air were studied by UV-vis spectroscopy. In addition, the Ag nanoparticles protected by N-acetyl-l-cysteine and glutathione reduced are used to investigate their antimicrobial efficacy and mechanism against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli, the antibacterial performance indicate that these Ag nanoparticles have superior stability and enhanced antibacterial activity compared to silver ions, it is believed that these Ag nanoparticles act as a promising antimicrobial material additive for practical applications.

Original languageEnglish
Pages (from-to)5130-5135
Number of pages6
JournalRSC Advances
Issue number10
Publication statusPublished - Jan 13 2014

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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