TY - JOUR
T1 - T-CELL INDUCERS OF SUPPRESSOR LYMPHOCYTES CONTROL LIVER-DIRECTED AUTOREACTIVITY
AU - Vento, Sandro
AU - Mcfarlane, Ian G.
AU - O'Brien, Charles J.
AU - Williams, Roger
AU - Eddleston, Adrian L.W.F.
N1 - Funding Information:
We thank Dr Alan Ting and Mr Craig Taylor, Nuffield Department of Surgery, Oxford, for HLA typing, and Dr Ronny Lundin, Phannacia AB, Uppsala, Sweden, for synthesising the peptide. The study was supported by the Coeliac Trust and the Wellcome Trust.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1987/4/18
Y1 - 1987/4/18
N2 - The sensitisation of helper T cells of patients with autoimmune chronic active hepatitis to a liver-cell membrane-expressed asialoglycoprotein receptor protein is shown to be associated with a defect of T cells that specifically induce suppressor lymphocytes. These lymphocytes are found in an activated state in the peripheral blood of healthy people and may form part of an immunoregulatory network which actively prevents autoimmunity.
AB - The sensitisation of helper T cells of patients with autoimmune chronic active hepatitis to a liver-cell membrane-expressed asialoglycoprotein receptor protein is shown to be associated with a defect of T cells that specifically induce suppressor lymphocytes. These lymphocytes are found in an activated state in the peripheral blood of healthy people and may form part of an immunoregulatory network which actively prevents autoimmunity.
UR - http://www.scopus.com/inward/record.url?scp=0023140245&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023140245&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(87)92860-1
DO - 10.1016/S0140-6736(87)92860-1
M3 - Article
C2 - 2882291
AN - SCOPUS:0023140245
VL - 329
SP - 886
EP - 888
JO - The Lancet
JF - The Lancet
SN - 0140-6736
IS - 8538
ER -