The Application of Multicomponent Ugi and Passerini Reactions for the One-Pot Synthesis of Pyrrolones and Butenolides

Anton A. Nechaev, Anatoly A. Peshkov, Vsevolod A. Peshkov, Erik V. Van Der Eycken

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A new protocol for the one-pot synthesis of pyrrolones and butenolides involving an isocyanide-based multicomponent reaction (Ugi or Passerini) followed by a triethylamine-promoted cycloisomerization is described.

Original languageEnglish
Article numberss-2016-t0067-op
Pages (from-to)2280-2286
Number of pages7
JournalSynthesis (Germany)
Volume48
Issue number14
DOIs
Publication statusPublished - Jul 15 2016
Externally publishedYes

Fingerprint

Cyanides
triethylamine

Keywords

  • butenolide
  • ethyl glyoxylate
  • Passerini reaction
  • propiolic acid
  • pyrrolone
  • Ugi reaction

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this

The Application of Multicomponent Ugi and Passerini Reactions for the One-Pot Synthesis of Pyrrolones and Butenolides. / Nechaev, Anton A.; Peshkov, Anatoly A.; Peshkov, Vsevolod A.; Van Der Eycken, Erik V.

In: Synthesis (Germany), Vol. 48, No. 14, ss-2016-t0067-op, 15.07.2016, p. 2280-2286.

Research output: Contribution to journalArticle

Nechaev, Anton A. ; Peshkov, Anatoly A. ; Peshkov, Vsevolod A. ; Van Der Eycken, Erik V. / The Application of Multicomponent Ugi and Passerini Reactions for the One-Pot Synthesis of Pyrrolones and Butenolides. In: Synthesis (Germany). 2016 ; Vol. 48, No. 14. pp. 2280-2286.
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