Aim: We researched frequency distribution of genotypes and alleles Lys198Asn of polymorphism of endothelin -1 gene associated with arterial hypertension development in Kazakh people Method: The research included 120 patients suffering arterial hypertension of 2-3 degree, average, high and very high degree of risk, and control group included 80 actually healthy person of Kazakh nationality. Result: The research discovered that development of arterial hypertension in the present ethnic group associated with polymorphism of endothelin-1 gene. Conclusion: At that, allele 198Asn and AsnAsn genotype of endothelin-1 gene act as marker of increased risk of arterial hypertension development.
|Translated title of the contribution||The association between polymorphism of lys198asn of endothelin-1 gene and arterial hypertension risk in Kazakh people|
|Number of pages||5|
|Journal||European Journal of General Medicine|
|Publication status||Published - Dec 21 2010|
- Blood pressure
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