Kazaklarda endotelin-1 geninin lys198asn polimorfizmi ile arteriyel hipertansiyon gelişme riski arasi{dotless}ndaki ilişki

Translated title of the contribution: The association between polymorphism of lys198asn of endothelin-1 gene and arterial hypertension risk in Kazakh people

A. U. Dzholdasbekova, A. E. Gaipov

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Aim: We researched frequency distribution of genotypes and alleles Lys198Asn of polymorphism of endothelin -1 gene associated with arterial hypertension development in Kazakh people Method: The research included 120 patients suffering arterial hypertension of 2-3 degree, average, high and very high degree of risk, and control group included 80 actually healthy person of Kazakh nationality. Result: The research discovered that development of arterial hypertension in the present ethnic group associated with polymorphism of endothelin-1 gene. Conclusion: At that, allele 198Asn and AsnAsn genotype of endothelin-1 gene act as marker of increased risk of arterial hypertension development.

Translated title of the contributionThe association between polymorphism of lys198asn of endothelin-1 gene and arterial hypertension risk in Kazakh people
Original languageTurkish
Pages (from-to)187-191
Number of pages5
JournalEuropean Journal of General Medicine
Volume7
Issue number2
DOIs
Publication statusPublished - Dec 21 2010
Externally publishedYes

Keywords

  • Blood pressure
  • Endothelin
  • Genes
  • Genetic
  • Hypertension

ASJC Scopus subject areas

  • Medicine(all)

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