TY - JOUR
T1 - The course and outcome of pregnancy in patient with concomitant Gilbert syndrome and hereditary spherocytosis
T2 - A unique case report
AU - Bapayeva, G.
AU - Togyzbayeva, K.
AU - Bekenova, A.
AU - Terzic, S.
AU - Terzic, M.
N1 - Publisher Copyright:
© 2019 S.O.G. CANADA Inc. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Gilbert syndrome (GS) is an autosomal dominant mild unconjugated hyperbilirubinemia. Hereditary spherocytosis (HS) is an inherited condition of non-immune heterogeneous hemolytic anemia. These two diseases can be very rarely diagnosed in one patient, but there is not one case reported in pregnant patient. The authors present a unique case of concomitant both diseases in pregnancy. The patient was 25- years-old, conceived spontaneously, and carefully observed throughout the pregnancy. Considering that both diseases might have a detrimental influence on pregnancy course and outcome, especially in this case with severe form of HS, the woman was hospitalized and carefully observed until the end of pregnancy. She delivered vaginally without any feto-maternal complications. In conclusion, coexisting GS and HS during pregnancy deserve careful monitoring and up-to-date treatment. This case report shows that a contemporary approach to the pregnant patient with GS and HS can result in the delivery of a healthy baby without any complications.
AB - Gilbert syndrome (GS) is an autosomal dominant mild unconjugated hyperbilirubinemia. Hereditary spherocytosis (HS) is an inherited condition of non-immune heterogeneous hemolytic anemia. These two diseases can be very rarely diagnosed in one patient, but there is not one case reported in pregnant patient. The authors present a unique case of concomitant both diseases in pregnancy. The patient was 25- years-old, conceived spontaneously, and carefully observed throughout the pregnancy. Considering that both diseases might have a detrimental influence on pregnancy course and outcome, especially in this case with severe form of HS, the woman was hospitalized and carefully observed until the end of pregnancy. She delivered vaginally without any feto-maternal complications. In conclusion, coexisting GS and HS during pregnancy deserve careful monitoring and up-to-date treatment. This case report shows that a contemporary approach to the pregnant patient with GS and HS can result in the delivery of a healthy baby without any complications.
KW - Gilbert syndrome
KW - Hereditary spherocytosis
KW - High-risk pregnancy
KW - Pregnancy outcome
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U2 - 10.12891/ceog4599.2019
DO - 10.12891/ceog4599.2019
M3 - Article
AN - SCOPUS:85067045841
SN - 0390-6663
VL - 46
SP - 320
EP - 322
JO - Clinical and Experimental Obstetrics and Gynecology
JF - Clinical and Experimental Obstetrics and Gynecology
IS - 2
ER -