The cytotoxic assessment of carbon adsorbents

L. M. Barnes, M. C. Murphy, M. Melillo, G. J. Phillips, J. G. Davies, A. W. Lloyd, S. V. Mikhalovsky

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A colony formation assay was used to assess the cytotoxic potential of a medical grade activated carbon adsorbent. It was observed that during extraction the adsorbent removed foetal calf serum (FCS) and other nutrients from the cell growth medium, making them unavailable to the cells during colony growth stage. The carbon adsorbent investigated was also found to be suitable for use in an extracorporeal device, for treatment of sepsis or acute renal failure. The results show that when carrying out cytotoxicity testing on highly porous adsorbent material, such as activated carbon, the methodology must be adapted to take into account the unusual material properties.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages631
Number of pages1
Publication statusPublished - 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

Fingerprint

Adsorbents
Carbon
Activated carbon
Cell growth
Cytotoxicity
Nutrients
Assays
Materials properties
Testing

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Barnes, L. M., Murphy, M. C., Melillo, M., Phillips, G. J., Davies, J. G., Lloyd, A. W., & Mikhalovsky, S. V. (2004). The cytotoxic assessment of carbon adsorbents. In Transactions - 7th World Biomaterials Congress (pp. 631)

The cytotoxic assessment of carbon adsorbents. / Barnes, L. M.; Murphy, M. C.; Melillo, M.; Phillips, G. J.; Davies, J. G.; Lloyd, A. W.; Mikhalovsky, S. V.

Transactions - 7th World Biomaterials Congress. 2004. p. 631.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Barnes, LM, Murphy, MC, Melillo, M, Phillips, GJ, Davies, JG, Lloyd, AW & Mikhalovsky, SV 2004, The cytotoxic assessment of carbon adsorbents. in Transactions - 7th World Biomaterials Congress. pp. 631, Transactions - 7th World Biomaterials Congress, Sydney, Australia, 5/17/04.
Barnes LM, Murphy MC, Melillo M, Phillips GJ, Davies JG, Lloyd AW et al. The cytotoxic assessment of carbon adsorbents. In Transactions - 7th World Biomaterials Congress. 2004. p. 631
Barnes, L. M. ; Murphy, M. C. ; Melillo, M. ; Phillips, G. J. ; Davies, J. G. ; Lloyd, A. W. ; Mikhalovsky, S. V. / The cytotoxic assessment of carbon adsorbents. Transactions - 7th World Biomaterials Congress. 2004. pp. 631
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