The longest period to recurrence of granulosa cell ovarian tumor: 41 years after initial diagnosis

M. Terzic; I. Likic Ladjevic; N. Ladjevic; S. Terzic; J. Dotlic; N. Arsenovic; A. S. Laganà; A. Vereczkey

doi:10.12892/ejgo4470.2018

The longest period to recurrence of granulosa cell ovarian tumor: 41 years after initial diagnosis

M. Terzic, I. Likic Ladjevic, N. Ladjevic, S. Terzic, J. Dotlic, N. Arsenovic, A. S. Laganà, A. Vereczkey

Research output: Contribution to journal › Article › peer-review

Abstract

Granulosa cell tumors (GCTs) are characterized by slow growth, local spread, and late recurrence. The authors report the case unique for both unusually large dimensions of the recurring tumor and the fact that it was confined only to the omentum, where it has recurred 41 years after the initial surgery including salpingo-oophorectomy. This is the longest reported period from initial diagnosis to the recurrence of GCT. This case report is important as it proves that recurrence of GCT is possible even after an extremely long period of time after the initial surgery, due to the nature of this tumor, and the inhibition of apoptosis process.

Original language	English
Pages (from-to)	800-802
Number of pages	3
Journal	European Journal of Gynaecological Oncology
Volume	39
Issue number	5
DOIs	https://doi.org/10.12892/ejgo4470.2018
Publication status	Published - Jan 1 2018

Keywords

Apoptosis
Granulosa cell tumor
Omentum
Ovary
Relapse

ASJC Scopus subject areas

Oncology
Obstetrics and Gynaecology

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The longest period to recurrence of granulosa cell ovarian tumor : 41 years after initial diagnosis. / Terzic, M.; Likic Ladjevic, I.; Ladjevic, N.; Terzic, S.; Dotlic, J.; Arsenovic, N.; Laganà, A. S.; Vereczkey, A.

In: European Journal of Gynaecological Oncology, Vol. 39, No. 5, 01.01.2018, p. 800-802.

Research output: Contribution to journal › Article › peer-review

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abstract = "Granulosa cell tumors (GCTs) are characterized by slow growth, local spread, and late recurrence. The authors report the case unique for both unusually large dimensions of the recurring tumor and the fact that it was confined only to the omentum, where it has recurred 41 years after the initial surgery including salpingo-oophorectomy. This is the longest reported period from initial diagnosis to the recurrence of GCT. This case report is important as it proves that recurrence of GCT is possible even after an extremely long period of time after the initial surgery, due to the nature of this tumor, and the inhibition of apoptosis process.",

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AU - Dotlic, J.

AU - Arsenovic, N.

AU - Laganà, A. S.

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