The hypothesis that soluble MHC Class I molecules could act as the vector which transports MHC-specific odours from the blood into the urine was put forward some ten years ago (Singh, Brown & Roser, 1987). Here, I summarise new evidence in favour of the hypothesis. 'We propose that the ability of MHC Class I molecules to associate in a selective way with other small molecules could also be the mechanism by which a unique mixture of volatile, endogenous metabolites is transported by [soluble] class I MHC glycoproteins from the blood into the urine' (Singh, Brown & Roser, 1987).
|Number of pages||3|
|Publication status||Published - Jul 1 1999|
- Carrier Proteins
- Chemoreceptor Cells
- Histocompatibility Antigens Class I
- Journal Article