The present status of the 'carrier hypothesis' for chemosensory recognition of genetic individuality

P B Singh

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

The hypothesis that soluble MHC Class I molecules could act as the vector which transports MHC-specific odours from the blood into the urine was put forward some ten years ago (Singh, Brown & Roser, 1987). Here, I summarise new evidence in favour of the hypothesis. 'We propose that the ability of MHC Class I molecules to associate in a selective way with other small molecules could also be the mechanism by which a unique mixture of volatile, endogenous metabolites is transported by [soluble] class I MHC glycoproteins from the blood into the urine' (Singh, Brown & Roser, 1987).

Original languageEnglish
Pages (from-to)231-3
Number of pages3
JournalGenetica
Volume104
Issue number3
Publication statusPublished - Jul 1 1999
Externally publishedYes

Keywords

  • Animals
  • Carrier Proteins
  • Chemoreceptor Cells
  • Histocompatibility Antigens Class I
  • Humans
  • Individuality
  • Smell
  • Journal Article
  • Review

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