TY - JOUR
T1 - Thoracolumbar interfascial plane block in spinal surgery
T2 - A systematic review with meta-analysis
AU - Abdildin, Yerkin G
AU - Salamat, Azamat
AU - Omarov, Temirlan
AU - Sultanova, Madina
AU - Krassavina, Yuliya
AU - Viderman, Dmitriy
N1 - Copyright © 2023. Published by Elsevier Inc.
PY - 2023/3/7
Y1 - 2023/3/7
N2 - OBJECTIVE: As the thoracolumbar interfascial plane (TLIP) block may be a promising alternative in spinal surgery, there is a need for timely meta-analysis of this method's effectiveness in different medical outcomes.METHOD: The meta-analysis of six randomized controlled studies on the application of TLIP block in spinal surgery was performed under the PRISMA guidelines. The primary outcome used for comparison was the mean difference (MD) of pain intensity scores at rest/in motion between patients receiving TLIP block and those receiving no block care.RESULTS: Our analysis favors TLIP block over no block (control group) for pain intensity at rest (MD with 95% CI is -1.14 [-1.29, -0.99], p-value < 0.00001, I
2 = 99%) and pain intensity in motion (MD with 95% CI is -1.49 [-1.73, -1.24], p-value < 0.00001, I
2 = 99%) on postoperative Day 1 (POD 1). Analysis also favors TLIP block in terms of cumulative fentanyl consumption on POD 1 (MD is -166.64 mcg with 95% CI [-204.48, -128.80], p-value < 0.00001, I
2 = 89%), postoperative side effects (risk ratio (RR) with 95% CI is 0.63 [0.44, 0.91], p-value = 0.01, I
2 = 0%), requests for supplementary/rescue analgesia (RR with 95% CI is 0.36 [0.23, 0.49], p-value < 0.00001, I
2 = 0%). The results are statistically significant.
CONCLUSION: The TLIP block reduces postoperative pain intensity, opioid consumption, side effects, and requests for rescue analgesia after spinal surgery more than the no-block alternative.
AB - OBJECTIVE: As the thoracolumbar interfascial plane (TLIP) block may be a promising alternative in spinal surgery, there is a need for timely meta-analysis of this method's effectiveness in different medical outcomes.METHOD: The meta-analysis of six randomized controlled studies on the application of TLIP block in spinal surgery was performed under the PRISMA guidelines. The primary outcome used for comparison was the mean difference (MD) of pain intensity scores at rest/in motion between patients receiving TLIP block and those receiving no block care.RESULTS: Our analysis favors TLIP block over no block (control group) for pain intensity at rest (MD with 95% CI is -1.14 [-1.29, -0.99], p-value < 0.00001, I
2 = 99%) and pain intensity in motion (MD with 95% CI is -1.49 [-1.73, -1.24], p-value < 0.00001, I
2 = 99%) on postoperative Day 1 (POD 1). Analysis also favors TLIP block in terms of cumulative fentanyl consumption on POD 1 (MD is -166.64 mcg with 95% CI [-204.48, -128.80], p-value < 0.00001, I
2 = 89%), postoperative side effects (risk ratio (RR) with 95% CI is 0.63 [0.44, 0.91], p-value = 0.01, I
2 = 0%), requests for supplementary/rescue analgesia (RR with 95% CI is 0.36 [0.23, 0.49], p-value < 0.00001, I
2 = 0%). The results are statistically significant.
CONCLUSION: The TLIP block reduces postoperative pain intensity, opioid consumption, side effects, and requests for rescue analgesia after spinal surgery more than the no-block alternative.
U2 - 10.1016/j.wneu.2023.02.140
DO - 10.1016/j.wneu.2023.02.140
M3 - Review article
C2 - 36894001
SN - 1878-8750
JO - World Neurosurgery
JF - World Neurosurgery
ER -