TY - JOUR
T1 - Three-component reaction of a 2-aminoazine, a 2-oxoaldehyde, and a cyclic 1,3-dicarbonyl compound for the synthesis of imidazo[1,2- a ]azine derivatives
AU - Peshkov, Vsevolod A.
AU - Peshkov, Anatoly A.
AU - Pereshivko, Olga P.
AU - Van Hecke, Kristof
AU - Zamigaylo, Lali L.
AU - Van Der Eycken, Erik V.
AU - Gorobets, Nikolay Yu
PY - 2014/10/13
Y1 - 2014/10/13
N2 - A three-component reaction of a 2-aminoazine, a 2-oxoaldehyde, and a cyclic 1,3-dicarbonyl compound providing access toward a novel class of imidazo[1,2-a]azine derivatives was developed and studied. The scope of the process was thoroughly explored under three different reaction conditions resulting in the generation of a small library of title compounds and highlighting the possibility of case-specific approach.
AB - A three-component reaction of a 2-aminoazine, a 2-oxoaldehyde, and a cyclic 1,3-dicarbonyl compound providing access toward a novel class of imidazo[1,2-a]azine derivatives was developed and studied. The scope of the process was thoroughly explored under three different reaction conditions resulting in the generation of a small library of title compounds and highlighting the possibility of case-specific approach.
KW - 1,3-dicarbonyl compounds
KW - 2-aminoazines
KW - 2-oxoaldehydes
KW - imidazo[1,2- a ]azines
KW - multicomponent reactions
UR - http://www.scopus.com/inward/record.url?scp=84907905365&partnerID=8YFLogxK
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U2 - 10.1021/co5000695
DO - 10.1021/co5000695
M3 - Article
C2 - 25170540
AN - SCOPUS:84907905365
VL - 16
SP - 535
EP - 542
JO - ACS Combinatorial Science
JF - ACS Combinatorial Science
SN - 2156-8952
IS - 10
ER -