Abstract
A novel TiO 2 nanowire bundle microelectrode based immunosensor was demonstrated as a more sensitive, specific, and rapid technology for detection of Listeria monocytogenes. TiO 2 nanowire bundle was prepared through a hydrothermal reaction of alkali with TiO 2 powder and connected to gold microelectrodes with mask welding. Monoclonal antibodies were immobilized on the surface of a TiO 2 nanowire bundle to specifically capture L. monocytogenes. Impedance change caused by the nanowire-antibody-bacteria complex was measured and correlated to bacterial number. This nanowire bundle based immunosensor could detect as low as 10 2 cfu/ml of L. monocytogenes in 1 h without significant interference from other foodborne pathogens.
| Original language | English |
|---|---|
| Pages (from-to) | 2625-2631 |
| Number of pages | 7 |
| Journal | Nano Letters |
| Volume | 8 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sep 2008 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Condensed Matter Physics
- Bioengineering
- Chemistry(all)
- Materials Science(all)
- Mechanical Engineering
Cite this
TiO 2 nanowire bundle microelectrode based impedance immunosensor for rapid and sensitive detection of Listeria monocytogenes. / Wang, Ronghui; Ruan, Chuanmin; Kanayeva, Damira; Lassiter, Kentu; Li, Yanbin.
In: Nano Letters, Vol. 8, No. 9, 09.2008, p. 2625-2631.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - TiO 2 nanowire bundle microelectrode based impedance immunosensor for rapid and sensitive detection of Listeria monocytogenes
AU - Wang, Ronghui
AU - Ruan, Chuanmin
AU - Kanayeva, Damira
AU - Lassiter, Kentu
AU - Li, Yanbin
PY - 2008/9
Y1 - 2008/9
N2 - A novel TiO 2 nanowire bundle microelectrode based immunosensor was demonstrated as a more sensitive, specific, and rapid technology for detection of Listeria monocytogenes. TiO 2 nanowire bundle was prepared through a hydrothermal reaction of alkali with TiO 2 powder and connected to gold microelectrodes with mask welding. Monoclonal antibodies were immobilized on the surface of a TiO 2 nanowire bundle to specifically capture L. monocytogenes. Impedance change caused by the nanowire-antibody-bacteria complex was measured and correlated to bacterial number. This nanowire bundle based immunosensor could detect as low as 10 2 cfu/ml of L. monocytogenes in 1 h without significant interference from other foodborne pathogens.
AB - A novel TiO 2 nanowire bundle microelectrode based immunosensor was demonstrated as a more sensitive, specific, and rapid technology for detection of Listeria monocytogenes. TiO 2 nanowire bundle was prepared through a hydrothermal reaction of alkali with TiO 2 powder and connected to gold microelectrodes with mask welding. Monoclonal antibodies were immobilized on the surface of a TiO 2 nanowire bundle to specifically capture L. monocytogenes. Impedance change caused by the nanowire-antibody-bacteria complex was measured and correlated to bacterial number. This nanowire bundle based immunosensor could detect as low as 10 2 cfu/ml of L. monocytogenes in 1 h without significant interference from other foodborne pathogens.
UR - http://www.scopus.com/inward/record.url?scp=54549090153&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=54549090153&partnerID=8YFLogxK
U2 - 10.1021/nl080366q
DO - 10.1021/nl080366q
M3 - Article
C2 - 18715043
AN - SCOPUS:54549090153
VL - 8
SP - 2625
EP - 2631
JO - Nano Letters
JF - Nano Letters
SN - 1530-6984
IS - 9
ER -