TiO 2 nanowire bundle microelectrode based impedance immunosensor for rapid and sensitive detection of Listeria monocytogenes

Ronghui Wang, Chuanmin Ruan, Damira Kanayeva, Kentu Lassiter, Yanbin Li

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

A novel TiO 2 nanowire bundle microelectrode based immunosensor was demonstrated as a more sensitive, specific, and rapid technology for detection of Listeria monocytogenes. TiO 2 nanowire bundle was prepared through a hydrothermal reaction of alkali with TiO 2 powder and connected to gold microelectrodes with mask welding. Monoclonal antibodies were immobilized on the surface of a TiO 2 nanowire bundle to specifically capture L. monocytogenes. Impedance change caused by the nanowire-antibody-bacteria complex was measured and correlated to bacterial number. This nanowire bundle based immunosensor could detect as low as 10 2 cfu/ml of L. monocytogenes in 1 h without significant interference from other foodborne pathogens.

Original languageEnglish
Pages (from-to)2625-2631
Number of pages7
JournalNano Letters
Volume8
Issue number9
DOIs
Publication statusPublished - Sep 1 2008

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

Fingerprint Dive into the research topics of 'TiO <sub>2</sub> nanowire bundle microelectrode based impedance immunosensor for rapid and sensitive detection of Listeria monocytogenes'. Together they form a unique fingerprint.

  • Cite this