Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses

Milan Terzic, Jelena Dotlic, Jovan Bila, Igor Pilic, Branka Nikolic, Dusica Kocijancic, Ivana Likic, Nebojsa Arsenovic, Tihomir Mihailovic, Diana Bugarski

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: To evaluate the reliability of ultrasound scan (US) findings in the preoperative assessment of the nature of adnexal masses infernales. Methods: After detailed history, a preoperative US examination was performed in all women. Tumor diameter, localization, the presence of solid, cystic and multilocular components, excrescences, metastasis and free fluid were assessed. Doppler scan was done and pulsatility (PI) and resistance indices (RI) were determined. These data were compared with postoperatively obtained histopathological findings and statistically analyzed. Results: The study included 609 women out of which 20.7% had malignant, 73.7% benign, and 5.6% borderline tumors. Patients with malignant tumors were oldest (p<0.001). There were significantly more positive US parameters in malignant than in benign tumors (p<0.001). Also, there were significant differences (p<0.001) between malignant, benign and borderline tumors regarding all examined US and Doppler parameters except tumor multilocularity. RI had sensitivity 75%, specificity 61.2%, positive predictive value (PPV) 42.70% and negative predictive value (NPV) 96.16%. PI had sensitivity 50%, specificity 35.3%, PPV 8.37% and NPV 25.93%. Sensitivity of US characteristics was 94.34%, specificity 30.62%, PPV 22.27% and NPV 96.25%. Conclusions: US pattern characteristics and Doppler parameters were found to be moderately reliable in discriminating malignant, benign and borderline adnexal tumors. Tumor of solid or mixed consistency, presence of ascites and excrescences were the best predictors of malignancy.

Original languageEnglish
Pages (from-to)862-869
Number of pages8
JournalJournal of B.U.ON.
Volume20
Issue number3
Publication statusPublished - Jan 1 2015
Externally publishedYes

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Neoplasms
Sensitivity and Specificity
Doppler Ultrasonography
Ascites
History
Neoplasm Metastasis

Keywords

  • Adnexal masses
  • Doppler
  • Malignancy
  • Ultrasound
  • Ultrasound pattern recognition

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

Cite this

Terzic, M., Dotlic, J., Bila, J., Pilic, I., Nikolic, B., Kocijancic, D., ... Bugarski, D. (2015). Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses. Journal of B.U.ON., 20(3), 862-869.

Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses. / Terzic, Milan; Dotlic, Jelena; Bila, Jovan; Pilic, Igor; Nikolic, Branka; Kocijancic, Dusica; Likic, Ivana; Arsenovic, Nebojsa; Mihailovic, Tihomir; Bugarski, Diana.

In: Journal of B.U.ON., Vol. 20, No. 3, 01.01.2015, p. 862-869.

Research output: Contribution to journalArticle

Terzic, M, Dotlic, J, Bila, J, Pilic, I, Nikolic, B, Kocijancic, D, Likic, I, Arsenovic, N, Mihailovic, T & Bugarski, D 2015, 'Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses', Journal of B.U.ON., vol. 20, no. 3, pp. 862-869.
Terzic, Milan ; Dotlic, Jelena ; Bila, Jovan ; Pilic, Igor ; Nikolic, Branka ; Kocijancic, Dusica ; Likic, Ivana ; Arsenovic, Nebojsa ; Mihailovic, Tihomir ; Bugarski, Diana. / Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses. In: Journal of B.U.ON. 2015 ; Vol. 20, No. 3. pp. 862-869.
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abstract = "Purpose: To evaluate the reliability of ultrasound scan (US) findings in the preoperative assessment of the nature of adnexal masses infernales. Methods: After detailed history, a preoperative US examination was performed in all women. Tumor diameter, localization, the presence of solid, cystic and multilocular components, excrescences, metastasis and free fluid were assessed. Doppler scan was done and pulsatility (PI) and resistance indices (RI) were determined. These data were compared with postoperatively obtained histopathological findings and statistically analyzed. Results: The study included 609 women out of which 20.7{\%} had malignant, 73.7{\%} benign, and 5.6{\%} borderline tumors. Patients with malignant tumors were oldest (p<0.001). There were significantly more positive US parameters in malignant than in benign tumors (p<0.001). Also, there were significant differences (p<0.001) between malignant, benign and borderline tumors regarding all examined US and Doppler parameters except tumor multilocularity. RI had sensitivity 75{\%}, specificity 61.2{\%}, positive predictive value (PPV) 42.70{\%} and negative predictive value (NPV) 96.16{\%}. PI had sensitivity 50{\%}, specificity 35.3{\%}, PPV 8.37{\%} and NPV 25.93{\%}. Sensitivity of US characteristics was 94.34{\%}, specificity 30.62{\%}, PPV 22.27{\%} and NPV 96.25{\%}. Conclusions: US pattern characteristics and Doppler parameters were found to be moderately reliable in discriminating malignant, benign and borderline adnexal tumors. Tumor of solid or mixed consistency, presence of ascites and excrescences were the best predictors of malignancy.",
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AU - Dotlic, Jelena

AU - Bila, Jovan

AU - Pilic, Igor

AU - Nikolic, Branka

AU - Kocijancic, Dusica

AU - Likic, Ivana

AU - Arsenovic, Nebojsa

AU - Mihailovic, Tihomir

AU - Bugarski, Diana

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N2 - Purpose: To evaluate the reliability of ultrasound scan (US) findings in the preoperative assessment of the nature of adnexal masses infernales. Methods: After detailed history, a preoperative US examination was performed in all women. Tumor diameter, localization, the presence of solid, cystic and multilocular components, excrescences, metastasis and free fluid were assessed. Doppler scan was done and pulsatility (PI) and resistance indices (RI) were determined. These data were compared with postoperatively obtained histopathological findings and statistically analyzed. Results: The study included 609 women out of which 20.7% had malignant, 73.7% benign, and 5.6% borderline tumors. Patients with malignant tumors were oldest (p<0.001). There were significantly more positive US parameters in malignant than in benign tumors (p<0.001). Also, there were significant differences (p<0.001) between malignant, benign and borderline tumors regarding all examined US and Doppler parameters except tumor multilocularity. RI had sensitivity 75%, specificity 61.2%, positive predictive value (PPV) 42.70% and negative predictive value (NPV) 96.16%. PI had sensitivity 50%, specificity 35.3%, PPV 8.37% and NPV 25.93%. Sensitivity of US characteristics was 94.34%, specificity 30.62%, PPV 22.27% and NPV 96.25%. Conclusions: US pattern characteristics and Doppler parameters were found to be moderately reliable in discriminating malignant, benign and borderline adnexal tumors. Tumor of solid or mixed consistency, presence of ascites and excrescences were the best predictors of malignancy.

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