Viral Infections and Autoimmune Hepatitis

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Viruses have been proposed as triggers for several autoimmune diseases-the most cited examples being B3 Coxsackie virus for myocarditis and B4 Coxsackie virus, cytomegalovirus (CMV) and rubella for type 1 diabetes mellitus. Autoimmune hepatitis is no exception, but a role for a few viruses has been convincingly shown only in rare cases of AH type 1, and is unconvincing in AH type 2-the very form where one of the most held views in modern immunology, that is molecular mimicry, has been repeatedly invoked in the latest 14 years. This chapter argues that even in patients with a genetic predisposition, a trigger must intervene at the "fight" time for the disease to develop; perhaps this "fight" time has to do with sexual hormones fluctuations or with concurrent drug administration; however, no clues are available in this respect.

Original languageEnglish
Title of host publicationInfection and Autoimmunity, 2nd edition
PublisherElsevier
Pages221-227
Number of pages7
ISBN (Print)9780444512710
DOIs
Publication statusPublished - 2004
Externally publishedYes

Fingerprint

Autoimmune Hepatitis
Enterovirus
Virus Diseases
Molecular Mimicry
Viruses
Rubella
Myocarditis
Genetic Predisposition to Disease
Allergy and Immunology
Cytomegalovirus
Type 1 Diabetes Mellitus
Autoimmune Diseases
Hormones
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Immunology and Microbiology(all)

Cite this

Vento, S., & Cainelli, F. (2004). Viral Infections and Autoimmune Hepatitis. In Infection and Autoimmunity, 2nd edition (pp. 221-227). Elsevier. https://doi.org/10.1016/B978-044451271-0.50019-3

Viral Infections and Autoimmune Hepatitis. / Vento, Sandro; Cainelli, Francesca.

Infection and Autoimmunity, 2nd edition. Elsevier, 2004. p. 221-227.

Research output: Chapter in Book/Report/Conference proceedingChapter

Vento, S & Cainelli, F 2004, Viral Infections and Autoimmune Hepatitis. in Infection and Autoimmunity, 2nd edition. Elsevier, pp. 221-227. https://doi.org/10.1016/B978-044451271-0.50019-3
Vento S, Cainelli F. Viral Infections and Autoimmune Hepatitis. In Infection and Autoimmunity, 2nd edition. Elsevier. 2004. p. 221-227 https://doi.org/10.1016/B978-044451271-0.50019-3
Vento, Sandro ; Cainelli, Francesca. / Viral Infections and Autoimmune Hepatitis. Infection and Autoimmunity, 2nd edition. Elsevier, 2004. pp. 221-227
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